What does punctate lesion mean?

Abstract. Background: Punctate white matter lesions (PWMLs) are small focal patches of increased signal intensity (SI) on T1- and decreased SI on T2-weighted magnetic resonance imaging (MRI).

What does punctate mean on an MRI?

Last Updated: October 2, 2020. Time to read: 5 minutes. White matter hyperintensities (WMHs) are lesions in the brain that show up as areas of increased brightness when visualised by T2-weighted magnetic resonance imaging (MRI).

Can MS lesions be punctate?

The lesions can be punctate or patchy and are more common in the supratentorial white matter where they can be present at any site, though most often are subcortical rather than periventricular.

What is punctate enhancement?

Introduction: Cerebral punctate and curvilinear gadolinium enhancements (PCGE) correspond to opacification of small vessel lumen or its perivascular areas in case of blood-brain barrier (BBB) disruption.

Does everyone have white matter lesions?

Combining these three studies together, it is clear that small (punctate) white matter lesions are extremely common, they are found in roughly half of the otherwise healthy population in their 40’s, and WML increase with age.

What does punctate calcification mean?

Punctate calcifications are a subset of round calcifications and, by definition, are <0.5 mm in size. Both these types of calcifications are considered typically benign when regional or diffuse in distribution.

What does punctate mean in medical terms?

Medical Definition of punctate (Entry 1 of 2) : characterized by dots or points punctate skin lesions. Other Words from punctate.

Do lesions always mean MS?

It’s not known why some people with MS may have more lesions in their brain than their spinal cord, or vice versa. However, it should be noted that spinal lesions do not necessarily indicate a diagnosis of MS, and can sometimes lead to a misdiagnosis of MS.

What is enhancement on brain MRI?

Purpose. Miliary enhancement refers to the presence of multiple small, monomorphic, enhancing foci on T1-weighted post-contrast MRI images. In the absence of a clear clinical presentation, a broad differential diagnosis may result in invasive procedures and possibly brain biopsy for diagnostic purposes.

Are white matter lesions serious?

Serious consequences of periventricular white matter lesions — this is the scary part. There is strong evidence that cerebral white matter lesions impair brain function, and in particular impair thinking ability and walking.

Can a punctate foci be benign or malignant?

While they are generally benign, approximately 1 percent of punctate foci of the bone are malignant, according to Medscape. Punctate foci lesions found in the brain, however, can be a sign of possible multiple sclerosis. These lesions are seen during an MRI scan of the brain and show up as pinpoint lesions within…

Where do you find punctate foci in the body?

Punctate foci are focal points of tiny spots or depressions. Punctate foci are seen in radiology exam results and denote the presence of possible disease. Punctate foci are commonly seen in the spine and brain. Punctate foci of the bone generally occur in the central spinal column and skull,…

Where can I find PubMed articles on punctate palmoplantar keratoderma type I?

PubMed is a searchable database of medical literature and lists journal articles that discuss Punctate palmoplantar keratoderma type I. Click on the link to view a sample search on this topic. Questions sent to GARD may be posted here if the information could be helpful to others.