What causes re-expansion pulmonary edema?

Key points. Re-expansion pulmonary edema is an uncommon complication following drainage of a pneumothorax or pleural effusion. Clinical presentations include cough, chest discomfort and hypoxemia; if the edema is severe, shock and death may ensue. Symptoms are usually noted within 24 hours after thoracentesis.

What is re-expansion pulmonary Oedema?

Reexpansion pulmonary edema (RPE) is a relatively rare condition which develops when a collapsed lung is allowed to expand suddenly. Histological abnormalities of the pulmonary micro-vessels as well as mechanical stress exerted during reexpansion are implicated in the pathogenesis of this disorder.

Can pulmonary edema reoccur?

Conclusions: Many patients with flash pulmonary edema have preserved systolic left ventricular function and coronary artery disease. Flash pulmonary edema frequently reoccurs in association with marked systolic hypertension, even after coronary revascularization.

What is reperfusion pulmonary edema?

Reperfusion pulmonary edema (also known as reimplantation response) is a form of non-cardiogenic pulmonary edema usually seen within 48 hours after lung transplantation. Reperfusion edema usually resolves over a period of days to months, usually within 1-2 weeks.

What’s the difference between pulmonary edema and pleural effusion?

Unlike pulmonary edema, in which fluid collects inside your lungs, pleural effusion is when it builds up in the layers of tissue that line the outside of your lungs and the inside of your chest. Symptoms include chest pain, shortness of breath, and a dry cough.

Is flash pulmonary edema acute?

Flash pulmonary edema (FPE) is a general clinical term used to describe a particularly dramatic form of acute decompensated heart failure.

What is the mortality rate of pulmonary edema?

The hospital mortality rate was 46% (12 of 26 patients) in the presence of AMI and 6% (1 of 18) in its absence (p = 0.006). Long-term follow-up of all hospital survivors revealed that 8 of 30 (27%) had died at 1 year and that 21 of 30 patients (70%) had died at 6 years.

How often does re-expansion pulmonary oedema occur?

Re-expansion pulmonary oedema is an uncommon complication occurring in less than 1% of cases where a lung has been rapidly re-expanded after being passively collapsed by a large pleural effusion or a pneumothorax.

When does a collapsed lung cause pulmonary edema?

Introduction. Reexpansion pulmonary edema (RPE) is a relatively rare condition which develops when a collapsed lung is allowed to expand suddenly. Histological abnormalities of the pulmonary micro-vessels as well as mechanical stress exerted during reexpansion are implicated in the pathogenesis of this disorder.

What happens when a collapsed lung is allowed to expand?

Reexpansion pulmonary edema (RPE) is a relatively rare condition which develops when a collapsed lung is allowed to expand suddenly. Histological abnormalities of the pulmonary micro-vessels as well as mechanical stress exerted during reexpansion are implicated in the pathogenesis of this disorder.

Can a pneumothorax cause a re-expansion lung injury?

Re-expansion lung injury/pulmonary oedema can occur after drainage of pneumothorax. It is more common in large pneumothoraces that have been present for a number of days. The pathophysiology is complex and poorly understood. It is usually self-limiting but some patients may require supportive treatment.