What is quinine sulfate dihydrate used for?

Quinine Sulfate Capsules, USP is an antimalarial drug indicated only for treatment of uncomplicated Plasmodium falciparum malaria.

What are the side effects of quinine sulphate?

Symptoms: Quinine overdosage may lead to serious side effects including irreversible visual loss, and can be fatal. Symptoms include vomiting, tinnitus, deafness, headache, vasodilation and visual disturbance.

What happens if you take too much quinine?

Some susceptible people develop a dangerous blood disorder after even small doses of quinine. Symptoms of quinine toxicity include digestive upset, headache, ringing in the ears, visual disturbances, skin rash and arrhythmias.

How much quinine can you take daily?

Adults and children 16 years of age and older—648 milligrams (mg) (2 capsules) every 8 hours for 7 days. Children younger than 16 years of age—Use and dose must be determined by your doctor.

How much quinine is safe?

Tonic water contains no more than 83 mg of quinine per liter—a much lower concentration than the 500 to 1,000 mg in the therapeutic dose of quinine tablets. Drinking a few ounces of tonic water shouldn’t be harmful, but it isn’t likely to prevent your leg cramps.

Do doctors still prescribe quinine?

Doctors continued to prescribe quinine sulfate for restless legs as well as leg cramps. Now, however, the FDA is cracking down. Soon, only one brand of quinine will be allowed on the market. Qualaquin is approved only for treating certain types of malaria, and it costs more than $4 per pill.

How to report side effects of quinine sulfate dihydrate?

You may report side effects to Health Canada at 1-866-234-2345. Consult your pharmacist or physician. Consult your pharmacist or physician. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Does Quinine Sulfate Dihydrate Powder interact with other drugs you are taking?

What is the mechanism of action of quinine sulfate?

Quinine Sulfate is the sulfate salt form of the quinidine alkaloid isolate quinine. Quinine has many mechanisms of action, including reduction of oxygen intake and carbohydrate metabolism; disruption of DNA replication and transcription via DNA intercalation; and reduction of the excitability…

Are there any antimalarial capsules for quinine sulfate?

Indications and Usage for Quinine Sulfate Capsules. Quinine Sulfate, USP is an antimalarial drug indicated only for treatment of uncomplicated Plasmodium falciparum malaria. Quinine Sulfate oral capsules are not approved for: Treatment of severe or complicated P. falciparum malaria. Prevention of malaria.

What happens if you take quinine sulfate with mefloquine?

Concomitant administration of quinine sulfate with the antimalarial drugs, mefloquine or halofantrine, may result in electrocardiographic abnormalities, including QT prolongation, and increase the risk for torsades de pointes or other serious ventricular arrhythmias.