What is MDA MB 468 cell line?

2020-03-28 by No Comments

What is MDA MB 468 cell line?

From Wikipedia, the free encyclopedia. MDA-MB-468 is a cell line that was isolated from a 51-year-old female human in 1977, and is commonly used in breast cancer research.

What is MCF7 cell line?

MCF-7 is a human breast cancer cell line with estrogen, progesterone and glucocorticoid receptors [26]. It is derived from the pleural effusion of a 69-year-old Caucasian metastatic breast cancer (adenocarcinoma) in 1970 by Dr Soule of the Michigan Cancer Foundation, Detroit, MI [27].

What are bt474 cells?

A human breast tumor cell line (BT-474) that supports mouse mammary tumor virus replication. In Vitro 15: 723-729, 1979. PubMed: 94035. Littlewood-Evans AJ, et al. The osteoclast-associated protease cathepsin K is expressed in human breast carcinoma.

Is MCF7 invasive?

Though MCF7 is categorized as poorly invasive, its migration in the 2D surface is found to be comparable to the highly invasive MDA MB 231 in the current study.

What type of cells are MCF7 cells?

MCF-7 is an adherent, epithelial luminal cell line positive for estrogen and progesterone receptors. Although they are referred to as hormone-dependent, the minimal amount of steroid hormones present in serum is sufficient to ensure cell growth.

What is the survival rate of TNBC?

According to the American Cancer Society, the overall 5-year relative survival rate for TNBC is 77 percent. However, an individual’s outlook depends on many factors, including the stage of the cancer and the grade of the tumor.

What can MDA-MB-468 cells be used for?

MDA-MB-468 cells were extracted from a pleural effusion of mammary gland and breast tissues, and have proven useful for the study of metastasis, migration, and breast cancer proliferation.

How are MDA-MB-468 cells plated in 96 well plates?

MDA-MB-468 cells (5 × 10 3 cells/well) were plated into 96-well plates and allowed to adhere overnight. 2. The cells were incubated with 100 pM of CyMe-Pan-Duo and CyEt-Pan-Duo for 24 h, the media was replaced, and the cells were exposed to varied doses of 690 or 780 nm light from LED sources.

Who was the donor of the G6PD cell line?

The cell line was isolated in 1977 by Relda Cailleau, et al., from a pleural effusion of a 51-year-old Black female patient with metastatic adenocarcinoma of the breast. Although the tissue donor was heterozygous for G6PD alleles, the cell line consistently showed only the G6PD A phenotype.